Infectious salmon anaemia virus (ISAV) mucosal infection in Atlantic salmon

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Infectious salmon anaemia virus (ISAV) mucosal infection in Atlantic salmon

All viruses infecting fish must cross the surface mucosal barrier to successfully enter a host. Infectious salmon anaemia virus (ISAV), the causative agent of the economically important infectious salmon anaemia (ISA) in Atlantic salmon, Salmo salar L., has been shown to use the gills as its entry point. However, other entry ports have not been investigated despite the expression of virus recep...

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Monitoring the immune response in fish over the progression of a disease is traditionally carried out by experimental infection whereby animals are killed at regular intervals and samples taken. We describe here a novel approach to infectiology for salmonid fish where blood samples are collected repeatedly in a small group of PIT-tagged animals. This approach contributes to the reduction of ani...

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Infectious salmon anaemia virus (ISAV): Evolution, genotyping, reservoirs and transmission

Infectious salmon anaemia virus, ISA virus (Isavirus, Orthomyxoviridae), emerged in Norwegian salmon culture in the mid-80s. The genome consists of eight segments coding for at least 10 proteins. ISA viruses show a lot of similarities with influenza A viruses, but differ in many important aspects like number of hosts, host population structure, and transmission. The only known hosts and reservo...

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Isolation of infectious salmon anemia virus (ISAV) from Atlantic salmon in New Brunswick, Canada.

Infectious salmon anemia virus (ISAV) was isolated at a marine grow-out site in New Brunswick, Canada, from Atlantic salmon Salmo salar which experienced mortalities due to hemorrhagic kidney syndrome (HKS). Of 20 fish sampled in this study, 14 showed histologically various degrees of interstitial hemorrhaging, tubular epithelial degeneration and necrosis, and tubular casts in the posterior kid...

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Atlantic salmon Salmo salar L. were injected intraperitoneally with infectious salmon anaemia virus (ISAV)-infective tissue homogenate to clarify the tissue distribution of ISAV in a time course study. Fish were sampled at 11 different intervals between 1 and 40 d post-infection (p.i.) and mid-kidney, head kidney, liver, spleen, intestine, gills, muscle and heart were tested for the presence of...

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ژورنال

عنوان ژورنال: Veterinary Research

سال: 2015

ISSN: 1297-9716

DOI: 10.1186/s13567-015-0265-1